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Effect and Dosage of Clenbuterol :
Clenbuterol is a β2 agonist with some structural and pharmacological similarities to epinephrine and salbutamol, but its effects are more potent and longer-lasting as a stimulant and thermogenic drug. It causes an increase in aerobic capacity, central nervous system stimulation, and an increase in blood pressure and oxygen transportation. It increases the rate at which body fat is metabolized while increasing the body’s BMR. It is commonly used for smooth muscle-relaxant properties. This means it is a bronchodilator and tocolytic.
Clenbuterol is usually used in dosages from 20-60 micrograms (μg) a day when prescribed. A dose of about 20 μg (women) or 40 μg (men) should never be exceeded in a day.
Clenbuterol is also prescribed for treatment of horses; however, equine use is usually the liquid form of clenbuterol.
Human Use Of Clenbuterol :
Clenbuterol is approved for use in some countries, via prescription only, as a bronchodilator for asthma patients.Recently, though, the drug has been publicized for its off-label use as a weight-loss drug, similar to usage of other sympathomimetic amines such as ephedrine. It is commonly used as a slimming aid despite the lack of sufficient clinical testing either supporting or negating such use.
Is Clenbuterol Legal ?
Clenbuterol is not an ingredient of any therapeutic drug approved by the US Food and Drug Administration and is now banned for IOC-tested athletes. In the US, administration of clenbuterol to any animal that could be used as food for human consumption is banned by the FDA.
Use as performance-enhancing drug
As a β2 sympathomimetic, clenbuterol has also been used as a performance-enhancing drug. Cyclist Alberto Contador of Spain was banned for two years from professional cycling after testing positive for the drug at the 2010 Tour de France. He was later stripped of the 2010 title of the Tour de France and the 2011 title of the Giro d’Italia.However, CAS found that Contador did not take clenbuterol as a performance-enhancing drug, but probably tested positive due to a contaminated food supplement.
American swimmer Jessica Hardy tested positive at the US trials in 2008. She served a one-year suspension, having claimed she unknowingly took the drug in a contaminated food supplement. Former New York Mets clubhouse employee Kirk Radomski admitted in his plea deal to distributing clenbuterol to dozens of current and former Major League Baseball players and associates.
After finishing fourth in the K-2 1000 m event at the 2008 Summer Olympics in Beijing, Polish sprint canoer Adam Seroczyński was disqualified for taking this drug; and Chinese cyclist Li Fuyu tested positive for it at the Dwars door Vlaanderen race in Belgium on March 24, 2010.
In 2006, San Francisco Giants pitcher Guillermo Mota, while a member of the New York Mets, received a 50-game suspension after testing positive for clenbuterol. In 2012, MLB announced they were again suspending Mota for 100 games due a positive test for clenbuterol.
In 2010, St. Louis Cardinals minor-league shortstop Lainer Bueno received a 50-game suspension for the 2011 season as a result of testing positive for clenbuterol.
In 2011, players of the Mexico national football team were found with clenbuterol in their bloodstreams, but were acquitted by WADA after they claimed the clenbuterol came from contaminated food. FIFA has also claimed 109 players from the Under-17 World Cup in Mexico tested positive for this drug, because Mexican meat is contaminated.
In 2012, Canadian weightlifter Nick Roberts received a two-year sanction after a urine sample tested positive for clenbuterol.
Side Effects of Clenbuterol and Dangers of Clenbuterol :
Low blood pressure
High blood pressure